| COMPARISON OF OTHER METHODS vs ISO-CHEK® |
| Collection Technique |
ISO-CHEK®
Dual Filter
Cassette |
OSHA
42 5
Single Filter
Cassette |
NIOSH
5521 6
Impinger
|
| Monomer Oligomer Separation |
Yes |
No |
No |
| HDI,
TDI Monomer Free From Matrix Interference |
Yes |
No |
No |
| Derivatizing Reagent |
MAMA7 |
1-2PP8 |
1-2MPP9 |
| Stable Reagent (Room Temp) |
Yes |
No 1O |
No 11 |
| Handling Precautions |
None |
Refrig |
Refrig |
| Method of Analysis |
RP HPLC
w/UV, Fluor |
RP HPLC
w/UV,Fluor |
RP HPLC
w/UV,ECD |
| Sample Collection Time (minutes) |
15 |
60 |
15-240 |
| Sample Prep & Analysis Time (minutes) |
45 |
75 |
75 |
Quantitation Limit12
(10 sigma2)
2,6-TDI
2,4-TDI
1,6-HDI
MDI |
1.0
1.0
1.0
1.0/0.27 |
2.3
2.5
2.9
NA |
0.5
0.7
1.0
0.3 |
Limit of Detection 13
(3 sigma2)
2,6-TDI
2,4-TDI
1,6-HDI
MDI |
0.2
0.2
0.6
0.3/0.08 |
1.6
1.3
2.3
NA |
0.1
0.1
0.1
0.1 |
| Precision of Analysis (CV) |
0.02 |
0.009 |
Unknown 14 |
| Range Tested for Precision (mg/m3) |
1-280 |
70-280 |
NA 15 |
Reproducibility/Accuracy16
% Recovery
SD |
100.3-100.6
1- 1.6 |
100.5-105.4
1.6-2.4 |
Not
Determined |
